| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 3 |
|---|
| Ligand | BDBM17660 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_106389 (CHEMBL717244) |
|---|
| EC50 | 40000±n/a nM |
|---|
| Citation |  Knöpfel, T; Kuhn, R; Allgeier, H Metabotropic glutamate receptors: novel targets for drug development. J Med Chem38:1417-26 (1995) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metabotropic glutamate receptor 3 |
|---|
| Name: | Metabotropic glutamate receptor 3 |
|---|
| Synonyms: | GRM3_RAT | Gprc1c | Grm3 | Mglur3 | glutamate receptor, metabotropic 3 precursor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 98971.84 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P31422 |
|---|
| Residue: | 879 |
|---|
| Sequence: | MKMLTRLQILMLALFSKGFLLSLGDHNFMRREIKIEGDLVLGGLFPINEKGTGTEECGRI
NEDRGIQRLEAMLFAIDEINKDNYLLPGVKLGVHILDTCSRDTYALEQSLEFVRASLTKV
DEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSD
KSRYDYFARTVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLRNIC
IATAEKVGRSNIRKSYDSVIRELLQKPNARVVVLFMRSDDSRELIAAANRVNASFTWVAS
DGWGAQESIVKGSEHVAYGAITLELASHPVRQFDRYFQSLNPYNNHRNPWFRDFWEQKFQ
CSLQNKRNHRQVCDKHLAIDSSNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCD
AMKILDGKKLYKEYLLKINFTAPFNPNKGADSIVKFDTFGDGMGRYNVFNLQQTGGKYSY
LKVGHWAETLSLDVDSIHWSRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYL
VDEFTCMDCGPGQWPTADLSGCYNLPEDYIKWEDAWAIGPVTIACLGFLCTCIVITVFIK
HNNTPLVKASGRELCYILLFGVSLSYCMTFFFIAKPSPVICALRRLGLGTSFAICYSALL
TKTNCIARIFDGVKNGAQRPKFISPSSQVFICLGLILVQIVMVSVWLILETPGTRRYTLP
EKRETVILKCNVKDSSMLISLTYDVVLVILCTVYAFKTRKCPENFNEAKFIGFTMYTTCI
IWLAFLPIFYVTSSDYRVQTTTMCISVSLSGFVVLGCLFAPKVHIVLFQPQKNVVTHRLH
LNRFSVSGTATTYSQSSASTYVPTVCNGREVLDSTTSSL
|
|
|
|---|
| BDBM17660 |
|---|
| n/a |
|---|
| Name | BDBM17660 |
|---|
| Synonyms: | (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid | 2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)propionic acid | CHEMBL279956 | Quisqualate | Quisqualate, L | quisqualic acid |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C5H7N3O5 |
|---|
| Mol. Mass. | 189.1262 |
|---|
| SMILES | N[C@@H](Cn1oc(=O)[nH]c1=O)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
