| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
|---|
| Ligand | BDBM50058150 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_145567 (CHEMBL749571) |
|---|
| Ki | 1029±n/a nM |
|---|
| Citation |  Ohkawa, S; DiGiacomo, B; Larson, DL; Takemori, AE; Portoghese, PS 7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors. J Med Chem40:1720-5 (1997) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Kappa-type opioid receptor |
|---|
| Name: | Kappa-type opioid receptor |
|---|
| Synonyms: | KOR-1 | MSL-1 | OPIATE Kappa | OPRK_MOUSE | Oprk1 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 42656.78 |
|---|
| Organism: | Mus musculus (Mouse) |
|---|
| Description: | P33534 |
|---|
| Residue: | 380 |
|---|
| Sequence: | MESPIQIFRGDPGPTCSPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLESAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRV
RNTVQDPASMRDVGGMNKPV
|
|
|
|---|
| BDBM50058150 |
|---|
| n/a |
|---|
| Name | BDBM50058150 |
|---|
| Synonyms: | 7-(5',6'-Benzo-2'-spiroindanyl)naltrexone | CHEMBL49704 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C32H31NO4 |
|---|
| Mol. Mass. | 493.5928 |
|---|
| SMILES | Oc1ccc2CC3N(CC4CC4)CCC45C(Oc1c24)C(=O)C1(Cc2cc4ccccc4cc2C1)C[C@@]35O |TLB:36:35:18.4.5:7.13.12,THB:8:7:35:18.4.5,17:18:35:7.13.12| |
|---|
| Structure | 
|
|---|
Search and Browse
