| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Somatostatin receptor type 2 |
|---|
| Ligand | BDBM50454936 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_200366 (CHEMBL805714) |
|---|
| Ki | 53±n/a nM |
|---|
| Citation |  Yang, L; Guo, L; Pasternak, A; Mosley, R; Rohrer, S; Birzin, E; Foor, F; Cheng, K; Schaeffer, J; Patchett, AA Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists. J Med Chem41:2175-9 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Somatostatin receptor type 2 |
|---|
| Name: | Somatostatin receptor type 2 |
|---|
| Synonyms: | SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 41344.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P30874 |
|---|
| Residue: | 369 |
|---|
| Sequence: | MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
|
|
|
|---|
| BDBM50454936 |
|---|
| n/a |
|---|
| Name | BDBM50454936 |
|---|
| Synonyms: | CHEMBL2112222 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H38N6O3 |
|---|
| Mol. Mass. | 542.6718 |
|---|
| SMILES | NCCCCC(NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(CC1)C=Cc1ccccc21)C(N)=O |c:32| |
|---|
| Structure | 
|
|---|
Search and Browse
