| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Somatostatin receptor type 3 |
|---|
| Ligand | BDBM50064774 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_200506 (CHEMBL803851) |
|---|
| Ki | 3614±n/a nM |
|---|
| Citation |  Yang, L; Guo, L; Pasternak, A; Mosley, R; Rohrer, S; Birzin, E; Foor, F; Cheng, K; Schaeffer, J; Patchett, AA Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists. J Med Chem41:2175-9 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Somatostatin receptor type 3 |
|---|
| Name: | Somatostatin receptor type 3 |
|---|
| Synonyms: | SOMATOSTATIN SST3 | SS-3-R | SS3-R | SS3R | SSR-28 | SSR3_HUMAN | SSTR3 | Somatostatin receptor type 3 (SSTR3) |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 45855.97 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P32745 |
|---|
| Residue: | 418 |
|---|
| Sequence: | MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLL
GNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVM
AVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVV
FSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRV
WAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVA
LPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEE
SREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
|
|
|
|---|
| BDBM50064774 |
|---|
| n/a |
|---|
| Name | BDBM50064774 |
|---|
| Synonyms: | 1'N-[1-(3-aminomethylcyclohexylmethylcarbamoyl)-2-(1H-3-indolyl)-(1S)-ethyl]spiro[1H-indene-1,4'-(hexahydropyridine)]-1'-carboxamide | CHEMBL305279 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H41N5O2 |
|---|
| Mol. Mass. | 539.7109 |
|---|
| SMILES | NCC1CCCC(CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(CC2)C=Cc2ccccc32)C1 |c:34| |
|---|
| Structure | 
|
|---|
Search and Browse
