| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 5 |
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| Ligand | BDBM50064773 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_200530 (CHEMBL806600) |
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| Ki | 4470±n/a nM |
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| Citation |  Yang, L; Guo, L; Pasternak, A; Mosley, R; Rohrer, S; Birzin, E; Foor, F; Cheng, K; Schaeffer, J; Patchett, AA Spiro[1H-indene-1,4'-piperidine] derivatives as potent and selective non-peptide human somatostatin receptor subtype 2 (sst2) agonists. J Med Chem41:2175-9 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 5 |
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| Name: | Somatostatin receptor type 5 |
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| Synonyms: | SOMATOSTATIN SST5 | SS-5-R | SS5-R | SS5R | SSR5_HUMAN | SSTR5 | Somatostatin receptor type 5 (SSTR5) |
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| Type: | Enzyme |
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| Mol. Mass.: | 39218.02 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35346 |
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| Residue: | 364 |
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| Sequence: | MEPLFPASTPSWNASSPGAASGGGDNRTLVGPAPSAGARAVLVPVLYLLVCAAGLGGNTL
VIYVVLRFAKMKTVTNIYILNLAVADVLYMLGLPFLATQNAASFWPFGPVLCRLVMTLDG
VNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADV
QEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVRR
RSERKVTRMVLVVVLVFAGCWLPFFTVNIVNLAVALPQEPASAGLYFFVVILSYANSCAN
PVLYGFLSDNFRQSFQKVLCLRKGSGAKDADATEPRPDRIRQQQEATPPAHRAAANGLMQ
TSKL
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| BDBM50064773 |
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| n/a |
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| Name | BDBM50064773 |
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| Synonyms: | 1'N-[1-[3-aminomethyl-(1S,3R)-cyclohexylmethylcarbamoyl]-2-(1H-3-indolyl)-(1S)-ethyl]spiro[1H-indene-1,4'-(hexahydropyridine)]-1'-carboxamide | CHEMBL71723 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H41N5O2 |
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| Mol. Mass. | 539.7109 |
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| SMILES | NC[C@@H]1CCC[C@H](CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(CC2)C=Cc2ccccc32)C1 |c:34| |
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| Structure | 
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