| Reaction Details |
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 | Report a problem with these data |
| Target | Calpain-2 catalytic subunit |
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| Ligand | BDBM50065396 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_43871 (CHEMBL658531) |
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| Ki | 9±n/a nM |
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| Citation |  Chatterjee, S; Gu, ZQ; Dunn, D; Tao, M; Josef, K; Tripathy, R; Bihovsky, R; Senadhi, SE; O'Kane, TM; McKenna, BA; Mallya, S; Ator, MA; Bozyczko-Coyne, D; Siman, R; Mallamo, JP D-amino acid containing, high-affinity inhibitors of recombinant human calpain I. J Med Chem41:2663-6 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calpain-2 catalytic subunit |
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| Name: | Calpain-2 catalytic subunit |
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| Synonyms: | CAN2_HUMAN | CANP 2 | CANPL2 | CAPN2 | Calcium-activated neutral proteinase 2 | Calpain 2 | Calpain M-type | Calpain large polypeptide L2 | Calpain-2 (m-Calpain) | Calpain-2 catalytic subunit | Calpain-2 large subunit | Calpain1/2 | M-calpain | Millimolar-calpain | calpain |
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| Type: | Protein |
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| Mol. Mass.: | 79965.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 700 |
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| Sequence: | MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGF
KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI
LARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL
LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGC
SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDN
CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTK
MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQR
KMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPG
EYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQ
LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL
WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFD
NFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL
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| BDBM50065396 |
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| n/a |
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| Name | BDBM50065396 |
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| Synonyms: | (R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-ethanesulfonylamino-propionamide | CHEMBL89008 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26N2O5S |
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| Mol. Mass. | 418.507 |
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| SMILES | CCS(=O)(=O)N[C@H](COCc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C=O |
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| Structure | 
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