| Reaction Details |
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 | Report a problem with these data |
| Target | Transporter |
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| Ligand | BDBM50094791 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_140884 (CHEMBL748007) |
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| Ki | 27±n/a nM |
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| Citation |  Gu, XH; Yu, H; Jacobson, AE; Rothman, RB; Dersch, CM; George, C; Flippen-Anderson, JL; Rice, KC Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline. J Med Chem43:4868-76 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Transporter |
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| Name: | Transporter |
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| Synonyms: | Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66787.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1463061 |
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| Residue: | 597 |
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| Sequence: | MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLF
YMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLN
LPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDI
GLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNG
INAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTIN
CVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFL
MLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLT
LLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLL
FVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAY
GITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
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| BDBM50094791 |
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| n/a |
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| Name | BDBM50094791 |
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| Synonyms: | CHEMBL542500 | [3-(3,4-Dichloro-phenyl)-4-methoxy-indan-1-yl]-methyl-amine; hydrochloride |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17Cl2NO |
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| Mol. Mass. | 322.229 |
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| SMILES | CN[C@@H]1CC(c2c1cccc2OC)c1ccc(Cl)c(Cl)c1 |
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| Structure | 
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