| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Calpain-1 catalytic subunit |
|---|
| Ligand | BDBM50084623 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_217823 (CHEMBL821730) |
|---|
| IC50 | 28±n/a nM |
|---|
| Citation |  Leung, D; Abbenante, G; Fairlie, DP Protease inhibitors: current status and future prospects. J Med Chem43:305-41 (2000) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Calpain-1 catalytic subunit |
|---|
| Name: | Calpain-1 catalytic subunit |
|---|
| Synonyms: | CAN1_HUMAN | CANPL1 | CAPN1 | Calpain ยต-type | Calpain-1 (u-Calpain) | Calpain-1 catalytic subunit | Calpain1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 81880.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 714 |
|---|
| Sequence: | MSEEIITPVYCTGVSAQVQKQRARELGLGRHENAIKYLGQDYEQLRVRCLQSGTLFRDEA
FPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAA
IASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHS
AEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILK
ALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQVVSLIRMRNPWGE
VEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKS
RTIRKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFV
LALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINL
REVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQANLPDEQVLSE
EEIDENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRD
GNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELII
TRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA
|
|
|
|---|
| BDBM50084623 |
|---|
| n/a |
|---|
| Name | BDBM50084623 |
|---|
| Synonyms: | 4-Azido-1-(toluene-4-sulfonyl)-pyrrolidine-2-carboxylic acid (1-formyl-2-phenyl-ethyl)-amide | CHEMBL115073 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H23N5O4S |
|---|
| Mol. Mass. | 441.503 |
|---|
| SMILES | Cc1ccc(cc1)S(=O)(=O)N1CC(CC1C(=O)N[C@@H](Cc1ccccc1)C=O)N=[N+]=[N-] |
|---|
| Structure | 
|
|---|
Search and Browse
