| Reaction Details |
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 | Report a problem with these data |
| Target | Genome polyprotein |
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| Ligand | BDBM50065674 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_161095 (CHEMBL771556) |
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| EC50 | 56±n/a nM |
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| Citation |  Leung, D; Abbenante, G; Fairlie, DP Protease inhibitors: current status and future prospects. J Med Chem43:305-41 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Genome polyprotein |
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| Name: | Genome polyprotein |
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| Synonyms: | Human rhinovirus A protease | Human rhinovirus B 3A protease |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44361.04 |
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| Organism: | Human rhinovirus B |
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| Description: | ChEMBL_158953 |
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| Residue: | 401 |
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| Sequence: | AFRPCNVNTKIGNAKCCPFVCGKAVTFKDRSTCSTYNLSSSLHHILEEDKRRRQVVDVMS
AIFQGPISLDAPPPPAIADLLQSVRTPRVIKYCQIIMGHPAECQVERDLNIANSIIAIIA
NIISIAGIIFVIYKLFCSLQGPYSGEPKPKTKVPERRVVAQGPEEEFGRSILKNNTCVIT
TGNGKFTGLGIHDRILIIPTHADPGREVQVNGVHTKVLDSYDLYNRDGVKLEITVIQLDR
NEKFRDIRKYIPETEDDYPECNLALSANQDEPTIIKVGDVVSYGNILLSGNQTARMLKYN
YPTKSGYCGGVLYKIGQILGIHVGGNGRDGFSAMLLRSYFTGQIKVNKHATECGLPDIQT
IHTPSKTKLQPSVFYDVFPGSKEPAVLTDNDPRLEVNFKEA
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| BDBM50065674 |
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| n/a |
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| Name | BDBM50065674 |
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| Synonyms: | (E)-(S)-6-Carbamoyl-4-[(S)-2-((S)-2-cyclopentylsulfanylcarbonylamino-3,3-dimethyl-butyrylamino)-3-p-tolyl-propionylamino]-hex-2-enoic acid ethyl ester | 6-Carbamoyl-4-[2-(2-cyclopentylsulfanylcarbonylamino-3,3-dimethyl-butyrylamino)-3-p-tolyl-propionylamino]-hex-2-enoic acid ethyl ester | CHEMBL95145 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H46N4O6S |
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| Mol. Mass. | 602.785 |
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| SMILES | CCOC(=O)\C=C\[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(C)cc1)NC(=O)[C@@H](NC(=O)SC1CCCC1)C(C)(C)C |
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| Structure | 
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