| Reaction Details |
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 | Report a problem with these data |
| Target | Matrilysin |
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| Ligand | BDBM11863 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105052 (CHEMBL711566) |
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| Ki | 1200±n/a nM |
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| Citation |  Leung, D; Abbenante, G; Fairlie, DP Protease inhibitors: current status and future prospects. J Med Chem43:305-41 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Matrilysin |
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| Name: | Matrilysin |
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| Synonyms: | MMP7 | MMP7_HUMAN | MPSL1 | Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | Matrix metalloproteinase-7 (MMP7) | PUMP1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 29681.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P09237 |
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| Residue: | 267 |
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| Sequence: | MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLK
EMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDL
PHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAF
APGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGD
PQNFKLSQDDIKGIQKLYGKRSNSRKK
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| BDBM11863 |
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| n/a |
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| Name | BDBM11863 |
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| Synonyms: | 4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N-hydroxyoxane-4-carboxamide | CHEMBL440498 | RS 130830 | RS-130,830 | alpha-tetrahydropyran beta-sulfone 1B |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20ClNO6S |
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| Mol. Mass. | 425.883 |
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| SMILES | ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCOCC1 |
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| Structure | 
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