| Reaction Details |
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 | Report a problem with these data |
| Target | Renin |
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| Ligand | BDBM50084669 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_195962 (CHEMBL806856) |
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| IC50 | 500±n/a nM |
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| Citation |  Leung, D; Abbenante, G; Fairlie, DP Protease inhibitors: current status and future prospects. J Med Chem43:305-41 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Renin |
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| Name: | Renin |
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| Synonyms: | Angiotensinogenase | REN | RENI_HUMAN |
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| Type: | Enzyme |
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| Mol. Mass.: | 45058.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 406 |
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| Sequence: | MDGWRRMPRWGLLLLLWGSCTFGLPTDTTTFKRIFLKRMPSIRESLKERGVDMARLGPEW
SQPMKRLTLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRL
YTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEM
PALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSENSQSLGG
QIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISG
STSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKK
LCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR
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| BDBM50084669 |
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| n/a |
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| Name | BDBM50084669 |
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| Synonyms: | 8-(4-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}-piperidin-3-yloxymethyl)-1,2,3,4-tetrahydro-quinoline | CHEMBL424437 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H40N2O4 |
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| Mol. Mass. | 516.671 |
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| SMILES | COc1ccccc1COCCCOc1ccc(cc1)C1CCNCC1OCc1cccc2CCCNc12 |
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| Structure | 
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