| Reaction Details |
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 | Report a problem with these data |
| Target | Anionic trypsin |
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| Ligand | BDBM50037991 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_212176 (CHEMBL815151) |
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| Ki | 1900±n/a nM |
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| Citation |  Leung, D; Abbenante, G; Fairlie, DP Protease inhibitors: current status and future prospects. J Med Chem43:305-41 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Anionic trypsin |
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| Name: | Anionic trypsin |
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| Synonyms: | Anionic trypsin | TRY2_BOVIN | Trypsin II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26281.39 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_212177 |
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| Residue: | 247 |
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| Sequence: | MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVS
AAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVIN
ARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQIT
NNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQ
ETIAANS
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| BDBM50037991 |
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| n/a |
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| Name | BDBM50037991 |
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| Synonyms: | CHEMBL325166 | NAPSAGATRAN | Ro-46-6240 | {[(S)-3-[((S)-1-Carbamimidoyl-piperidin-3-ylmethyl)-carbamoyl]-2-(naphthalene-2-sulfonylamino)-propionyl]-cyclopropyl-amino}-acetic acid | {[3-[(1-Carbamimidoyl-piperidin-3-ylmethyl)-carbamoyl]-2-(naphthalene-2-sulfonylamino)-propionyl]-cyclopropyl-amino}-acetic acid(napsagatran(RO46-6240)) |
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| Type | Small organic molecule |
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| Emp. Form. | C26H34N6O6S |
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| Mol. Mass. | 558.65 |
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| SMILES | NC(=N)N1CCC[C@@H](CNC(=O)C[C@H](NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N(CC(O)=O)C2CC2)C1 |
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| Structure | 
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