| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50085922 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_61595 (CHEMBL675767) |
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| IC50 | 22000±n/a nM |
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| Citation |  Guzikowski, AP; Tamiz, AP; Acosta-Burruel, M; Hong-Bae, S; Cai, SX; Hawkinson, JE; Keana, JF; Kesten, SR; Shipp, CT; Tran, M; Whittemore, ER; Woodward, RM; Wright, JL; Zhou, ZL Synthesis of N-substituted 4-(4-hydroxyphenyl)piperidines, 4-(4-hydroxybenzyl)piperidines, and (+/-)-3-(4-hydroxyphenyl)pyrrolidines: selective antagonists at the 1A/2B NMDA receptor subtype. J Med Chem43:984-94 (2000) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50085922 |
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| n/a |
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| Name | BDBM50085922 |
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| Synonyms: | 4-(4-Hydroxy-phenyl)-1-(4-phenyl-butyl)-piperidin-4-ol | CHEMBL174632 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H27NO2 |
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| Mol. Mass. | 325.4446 |
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| SMILES | Oc1ccc(cc1)C1(O)CCN(CCCCc2ccccc2)CC1 |
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| Structure | 
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