Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat)) | BDBM50045050 (1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 17.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3 (RAT) | BDBM50045050 (1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT) | BDBM50045050 (1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2 (Rattus norvegicus (Rat)) | BDBM50045050 (1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 41 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-6 (RAT) | BDBM50045050 (1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-3 (RAT) | BDBM85683 (Co 2-6749 | Co-2-6749 | GMA-839 | WAY-141839) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 96 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-2 (Rattus norvegicus (Rat)) | BDBM85683 (Co 2-6749 | Co-2-6749 | GMA-839 | WAY-141839) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-1 (Rattus norvegicus (Rat)) | BDBM85683 (Co 2-6749 | Co-2-6749 | GMA-839 | WAY-141839) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT) | BDBM85683 (Co 2-6749 | Co-2-6749 | GMA-839 | WAY-141839) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 210 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-6 (RAT) | BDBM50045050 (1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM50045050 (1-(3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopen...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-6 (RAT) | BDBM85683 (Co 2-6749 | Co-2-6749 | GMA-839 | WAY-141839) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid receptor subunit alpha-4 (Rattus norvegicus (Rat)) | BDBM85683 (Co 2-6749 | Co-2-6749 | GMA-839 | WAY-141839) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PubMed | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by PDSP Ki Database | J Pharmacol Exp Ther 295: 337-45 (2000) BindingDB Entry DOI: 10.7270/Q2251GQJ | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255109 (CHEMBL4081196) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.00200 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255111 (CHEMBL4092961) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0110 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255122 (CHEMBL4059538) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255138 (CHEMBL4066361) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-3 (Rattus norvegicus) | BDBM50286739 (4-((1R,3S,5S,8R,10R,11R,13R,14S,17R)-1,5,11,14-tet...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta3 expressed in baculovirus infected Sf9 cell membranes using [gamma-32P]ATP as substrate prein... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255120 (CHEBI:38178 | STROPHANTHIDIN) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255119 (CHEMBL4071710) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50286739 (4-((1R,3S,5S,8R,10R,11R,13R,14S,17R)-1,5,11,14-tet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50056605 (7-Chloro-6-methyl-5-nitro-1,4-dihydro-quinoxaline-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys Inc. Curated by ChEMBL | Assay Description Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ... | J Med Chem 40: 730-8 (1997) Article DOI: 10.1021/jm960654b BindingDB Entry DOI: 10.7270/Q2NZ86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255140 (CHEMBL4076623) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255139 (CHEMBL4085219) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM46355 (DIGOXIN | MLS000069819 | SMR000059217 | US10668094...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50038161 (6,7-Dichloro-3-hydroxy-5-nitro-3,4-dihydro-1H-quin...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys Inc. Curated by ChEMBL | Assay Description Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ... | J Med Chem 40: 730-8 (1997) Article DOI: 10.1021/jm960654b BindingDB Entry DOI: 10.7270/Q2NZ86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50052635 (5,6,7-Trichloro-1H-quinoline-2,3,4-trione 3-oxime ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranes | J Med Chem 39: 3248-55 (1996) Article DOI: 10.1021/jm960214k BindingDB Entry DOI: 10.7270/Q2QC02KC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50056596 (7-Bromo-6-methyl-5-nitro-1,4-dihydro-quinoxaline-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 8.70 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys Inc. Curated by ChEMBL | Assay Description Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ... | J Med Chem 40: 730-8 (1997) Article DOI: 10.1021/jm960654b BindingDB Entry DOI: 10.7270/Q2NZ86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255128 (CHEMBL4067657) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM50369783 (CHEMBL1203902) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype. | J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255121 (CHEBI:4037 | CHEMBL1075788) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255117 (CHEMBL4072996) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50052629 (6,7-Dichloro-1H-quinoline-2,3,4-trione 3-oxime | C...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranes | J Med Chem 39: 3248-55 (1996) Article DOI: 10.1021/jm960214k BindingDB Entry DOI: 10.7270/Q2QC02KC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM50085922 (4-(4-Hydroxy-phenyl)-1-(4-phenyl-butyl)-piperidin-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype. | J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255116 (CHEMBL4074239) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM50085933 (4-[1-(5-Phenyl-pentyl)-pyrrolidin-3-yl]-phenol | C...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype. | J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM50085927 (4-[1-(2-Hydroxy-4-phenyl-butyl)-piperidin-4-yl]-ph...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype. | J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM50369786 (CHEMBL1201889) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype. | J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50056618 (6,7-Dibromo-5-nitro-1,4-dihydro-quinoxaline-2,3-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys Inc. Curated by ChEMBL | Assay Description Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ... | J Med Chem 40: 730-8 (1997) Article DOI: 10.1021/jm960654b BindingDB Entry DOI: 10.7270/Q2NZ86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM50369791 (CHEMBL1202296) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype. | J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM50079386 (4-[2-(4-Benzyl-piperidin-1-yl)-ethoxy]-phenol | 4-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytes | J Med Chem 42: 2993-3000 (1999) Article DOI: 10.1021/jm990246i BindingDB Entry DOI: 10.7270/Q2RX9B8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM50085929 (4-(4-Hydroxy-phenyl)-1-(2-hydroxy-4-phenyl-butyl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype. | J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT) | BDBM50079389 (4-{2-[4-(4-Methyl-benzyl)-piperidin-1-yl]-ethoxy}-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys, Inc. Curated by ChEMBL | Assay Description In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytes | J Med Chem 42: 2993-3000 (1999) Article DOI: 10.1021/jm990246i BindingDB Entry DOI: 10.7270/Q2RX9B8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50056595 (6,7-Dimethyl-5-nitro-1,4-dihydro-quinoxaline-2,3-d...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys Inc. Curated by ChEMBL | Assay Description Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ... | J Med Chem 40: 730-8 (1997) Article DOI: 10.1021/jm960654b BindingDB Entry DOI: 10.7270/Q2NZ86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50056620 (6-Chloro-7-ethyl-5-nitro-1,4-dihydro-quinoxaline-2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys Inc. Curated by ChEMBL | Assay Description Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ... | J Med Chem 40: 730-8 (1997) Article DOI: 10.1021/jm960654b BindingDB Entry DOI: 10.7270/Q2NZ86RJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1 (RAT) | BDBM50052627 (5,6,7-Trichloro-1,4-dihydro-quinoxaline-2,3-dione ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
CoCensys Inc. Curated by ChEMBL | Assay Description Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranes | J Med Chem 39: 3248-55 (1996) Article DOI: 10.1021/jm960214k BindingDB Entry DOI: 10.7270/Q2QC02KC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-3/beta-1 (Rattus norvegicus) | BDBM50286739 (4-((1R,3S,5S,8R,10R,11R,13R,14S,17R)-1,5,11,14-tet...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha3/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255108 (CHEMBL4077606) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255107 (CHEMBL4093925) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium/potassium-transporting ATPase subunit alpha-4/beta-1 (Rattus norvegicus) | BDBM50255114 (CHEMBL4072200) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Medicinal Chemistry and Institute for Therapeutics Discovery and Development, College of Pharmacy , University of Minnesota , Minneapolis , Minnesota 55414 , United States. Curated by ChEMBL | Assay Description Inhibition of recombinant rat Na+/K+-ATPase alpha4/beta1 expressed in baculovirus infected insect Sf9 cell membranes using [gamma-32P]ATP as substrat... | J Med Chem 61: 1800-1820 (2018) Article DOI: 10.1021/acs.jmedchem.7b00925 BindingDB Entry DOI: 10.7270/Q2T43WJH | |||||||||||
More data for this Ligand-Target Pair |
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