| Reaction Details |
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 | Report a problem with these data |
| Target | D(1B) dopamine receptor |
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| Ligand | BDBM50105090 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_61330 (CHEMBL675948) |
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| IC50 | 3660±n/a nM |
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| Citation |  Poulain, R; Horvath, D; Bonnet, B; Eckhoff, C; Chapelain, B; Bodinier, MC; Déprez, B From hit to lead. Analyzing structure-profile relationships. J Med Chem44:3391-401 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1B) dopamine receptor |
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| Name: | D(1B) dopamine receptor |
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| Synonyms: | D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5 |
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| Type: | Protein |
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| Mol. Mass.: | 52943.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21918 |
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| Residue: | 477 |
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| Sequence: | MLPPGSNGTAYPGQFALYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVL
VCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGAFCDVWVAFD
IMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNW
HRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAI
MIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSLRASIKKETKVLKTLSV
IMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIYA
FNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTP
GNREVDNDEEEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH
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| BDBM50105090 |
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| n/a |
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| Name | BDBM50105090 |
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| Synonyms: | 3-Methylcarbamoylmethyl-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-carboxylic acid 6-chloro-benzo[1,3]dioxol-5-ylmethyl ester | CHEMBL114825 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27ClN4O6 |
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| Mol. Mass. | 514.958 |
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| SMILES | CNC(=O)CN1CN(c2ccccc2)C2(CCN(CC2)C(=O)OCc2cc3OCOc3cc2Cl)C1=O |
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| Structure | 
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