| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine deaminase |
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| Ligand | BDBM50105935 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_30812 (CHEMBL645087) |
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| Ki | >800000±n/a nM |
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| Citation |  Hakimelahi, GH; Ly, TW; Moosavi-Movahedi, AA; Jain, ML; Zakerinia, M; Davari, H; Mei, HC; Sambaiah, T; Moshfegh, AA; Hakimelahi, S Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses. J Med Chem44:3710-20 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Adenosine deaminase |
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| Name: | Adenosine deaminase |
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| Synonyms: | ADA | ADA_BOVIN | Adenosine aminohydrolase |
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| Type: | Enzyme |
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| Mol. Mass.: | 40910.44 |
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| Organism: | Bos taurus (bovine) |
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| Description: | n/a |
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| Residue: | 363 |
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| Sequence: | MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
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|
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| BDBM50105935 |
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| n/a |
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| Name | BDBM50105935 |
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| Synonyms: | CHEMBL121723 | [2-(6-Amino-purin-9-yl)-ethoxymethyl]-phosphonic acid mono-[2-(3,4-dimethoxy-5-oxo-5H-furan-2-ylidene)-ethyl] ester |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20N5O8P |
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| Mol. Mass. | 441.3325 |
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| SMILES | COC1=C(OC)\C(OC1=O)=C\COP(O)(=O)COCCn1cnc2c(N)ncnc12 |c:2| |
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| Structure | 
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