Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Delta-type opioid receptor | ||
| Ligand | BDBM50001707 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_146333 (CHEMBL754765) | ||
| Ki | 610±n/a nM | ||
| Citation |  Metzger, TG; Paterlini, MG; Ferguson, DM; Portoghese, PS Investigation of the selectivity of oxymorphone- and naltrexone-derived ligands via site-directed mutagenesis of opioid receptors: exploring the"address" recognition locus. J Med Chem44:857-62 (2001) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Delta-type opioid receptor | |||
| Name: | Delta-type opioid receptor | ||
| Synonyms: | DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 40577.25 | ||
| Organism: | MOUSE | ||
| Description: | P32300 | ||
| Residue: | 372 | ||
| Sequence: |
| ||
| BDBM50001707 | |||
| n/a | |||
| Name | BDBM50001707 | ||
| Synonyms: | 10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one | 10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(oxymorphone) | 10,17-dihydroxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one(xymorphone) | 10,17-dihydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7,9,11(18)-trien-14-one | CHEMBL963 | Codoxy | Combunox | Numorphan | OXYMORPHONE | Opana | Oxycet | PERCODAN-DEMI | Percocet | Percodan | Roxicet | Roxilox | Roxiprin | Tylox | Tylox-325 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H19NO4 | ||
| Mol. Mass. | 301.3371 | ||
| SMILES | CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)CCC4=O)ccc5O |TLB:14:12:8.9.10:1.3.2,THB:13:12:8.9.10:1.3.2| | ||
| Structure | 
| ||