| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 2 |
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| Ligand | BDBM50306712 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_147745 (CHEMBL753285) |
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| EC50 | 15.9±n/a nM |
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| Citation |  Kim, HS; Ravi, RG; Marquez, VE; Maddileti, S; Wihlborg, AK; Erlinge, D; Malmsjö, M; Boyer, JL; Harden, TK; Jacobson, KA Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors. J Med Chem45:208-18 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 2 |
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| Name: | P2Y purinoceptor 2 |
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| Synonyms: | ATP receptor | P2RU1 | P2RY2 | P2RY2_HUMAN | P2U purinoceptor 1 | P2U1 | P2Y purinoceptor 2 | P2Y2 | Purinergic receptor | Purinergic receptor P2Y2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42299.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1455361 |
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| Residue: | 377 |
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| Sequence: | MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLC
RLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCS
ILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGR
VTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAK
RKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSC
LDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSR
RTESTPAGSENTKDIRL
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| BDBM50306712 |
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| n/a |
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| Name | BDBM50306712 |
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| Synonyms: | ((1R,2R,3S,4R,5S)-4-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,3-dihydroxybicyclo[3.1.0]hexan-1-yl)methyl tetrahydrogen triphosphate | CHEMBL606210 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17N2O14P3 |
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| Mol. Mass. | 494.179 |
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| SMILES | O[C@@H]1[C@H](O)[C@]2(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C[C@@H]2[C@H]1n1ccc(=O)[nH]c1=O |r| |
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| Structure | 
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