| Reaction Details |
|---|
 | Report a problem with these data |
| Target | P2Y purinoceptor 11 |
|---|
| Ligand | BDBM50409486 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_147735 (CHEMBL755046) |
|---|
| EC50 | 17250±n/a nM |
|---|
| Citation |  Kim, HS; Ravi, RG; Marquez, VE; Maddileti, S; Wihlborg, AK; Erlinge, D; Malmsjö, M; Boyer, JL; Harden, TK; Jacobson, KA Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors. J Med Chem45:208-18 (2001) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| P2Y purinoceptor 11 |
|---|
| Name: | P2Y purinoceptor 11 |
|---|
| Synonyms: | P2RY11 | P2Y purinoceptor 11 | P2Y11 | P2Y11_HUMAN | Purinergic receptor P2Y11 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40366.02 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1362532 |
|---|
| Residue: | 374 |
|---|
| Sequence: | MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRP
WHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFI
TCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNC
SVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTV
AEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPY
VGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATA
APKPSEPQSRELSQ
|
|
|
|---|
| BDBM50409486 |
|---|
| n/a |
|---|
| Name | BDBM50409486 |
|---|
| Synonyms: | CHEMBL2111533 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H18N5O12P3 |
|---|
| Mol. Mass. | 517.2189 |
|---|
| SMILES | Nc1ncnc2n(cnc12)[C@@H]1[C@H]2C[C@@]2(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |
|---|
| Structure | 
|
|---|
Search and Browse
