| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 3 |
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| Ligand | BDBM50114084 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_106832 (CHEMBL717673) |
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| Ki | 7.8±n/a nM |
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| Citation |  Kavarana, MJ; Trivedi, D; Cai, M; Ying, J; Hammer, M; Cabello, C; Grieco, P; Han, G; Hruby, VJ Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors. J Med Chem45:2644-50 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 3 |
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| Name: | Melanocortin receptor 3 |
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| Synonyms: | MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36044.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41968 |
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| Residue: | 323 |
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| Sequence: | MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVI
LAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIF
DSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFI
VYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKG
AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA
FRSLELRNTFREILCGCNGMNLG
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| BDBM50114084 |
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| n/a |
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| Name | BDBM50114084 |
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| Synonyms: | (O)C-(C6H4)-C(O)-c[His-D-Nal(2')-Arg-Trp-Lys]-NH2) (MK-7) | CHEMBL439188 |
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| Type | Small organic molecule |
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| Emp. Form. | C50H57N13O7 |
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| Mol. Mass. | 952.0705 |
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| SMILES | NC(=N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)c2ccccc2C(=O)NCCCC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O |
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| Structure | 
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