Reaction Details | |||
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Target | Delta-type opioid receptor | ||
Ligand | BDBM50122535 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_145336 (CHEMBL750571) | ||
IC50 | 8840±n/a nM | ||
Citation | Hanessian, S; Parthasarathy, S; Mauduit, M; Payza, K The power of visual imagery in drug design. Isopavines as a new class of morphinomimetics and their human opioid receptor binding activity. J Med Chem46:34-48 (2002) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Delta-type opioid receptor | |||
Name: | Delta-type opioid receptor | ||
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 40382.98 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. | ||
Residue: | 372 | ||
Sequence: |
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BDBM50122535 | |||
n/a | |||
Name | BDBM50122535 | ||
Synonyms: | 4,13-dibromo-16,17-dimethyl-17-azatetracyclo[7.6.2.02,7.010,15]heptadeca-2(7),3,5,12,14-pentaene | ||
Type | Small organic molecule | ||
Emp. Form. | C18H19Br2N | ||
Mol. Mass. | 409.158 | ||
SMILES | C[C@@H]1[C@@H]2C3=CC(Br)=CC[C@H]3[C@H](Cc3ccc(Br)cc23)N1C |wU:2.2,10.21,9.9,1.0,c:6,t:3,TLB:0:1:3.9:18.12.11,17:18:19.1:3.9,THB:20:19:3.9:18.12.11,8:9:19.1:18.12.11,13:12:19.1:3.9,(10.16,-3.34,;8.73,-3.89,;4.99,-2.64,;4.97,-1.1,;4.97,.44,;6.3,1.2,;6.3,2.74,;7.63,.44,;7.65,-1.1,;6.3,-1.87,;6.54,-5.74,;5,-5.74,;3.66,-4.97,;2.32,-5.74,;.99,-4.97,;.99,-3.43,;-.34,-2.66,;2.32,-2.66,;3.66,-3.43,;7.97,-5.23,;8.96,-6.4,)| | ||
Structure |