Reaction Details | |||
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Target | Delta-type opioid receptor | ||
Ligand | BDBM50122521 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_145336 (CHEMBL750571) | ||
IC50 | 2040±n/a nM | ||
Citation | Hanessian, S; Parthasarathy, S; Mauduit, M; Payza, K The power of visual imagery in drug design. Isopavines as a new class of morphinomimetics and their human opioid receptor binding activity. J Med Chem46:34-48 (2002) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Delta-type opioid receptor | |||
Name: | Delta-type opioid receptor | ||
Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 40382.98 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. | ||
Residue: | 372 | ||
Sequence: |
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BDBM50122521 | |||
n/a | |||
Name | BDBM50122521 | ||
Synonyms: | 17-cyclopropylmethyl-16-methyl-4,13-di(4-methylhexahydro-1-pyrazinyl)-(16R)-17-azatetracyclo[7.6.2.02,7.010,15]heptadeca-2(7),3,5,12,14-pentaene | ||
Type | Small organic molecule | ||
Emp. Form. | C31H45N5 | ||
Mol. Mass. | 487.7225 | ||
SMILES | C[C@@H]1[C@@H]2C3=CC(=CC[C@H]3[C@H](Cc3ccc(cc23)N2CCN(C)CC2)N1CC1CC1)N1CCN(C)CC1 |wU:2.2,9.27,8.7,1.0,c:5,t:3,TLB:0:1:3.8:16.11.10,15:16:24.1:3.8,THB:7:8:24.1:16.11.10,25:24:3.8:16.11.10,12:11:24.1:3.8,(18.32,-10.24,;17.23,-11.34,;13.4,-10.08,;13.4,-8.52,;13.4,-6.98,;14.73,-6.21,;16.06,-6.98,;16.06,-8.52,;14.73,-9.29,;14.94,-13.17,;13.4,-13.17,;12.07,-12.4,;10.74,-13.17,;9.4,-12.4,;9.4,-10.85,;10.74,-10.08,;12.07,-10.85,;8.06,-10.06,;6.7,-10.83,;5.35,-10.04,;5.37,-8.48,;4.04,-7.7,;6.73,-7.71,;8.06,-8.5,;16.39,-12.61,;17.34,-13.81,;16.76,-15.24,;16.36,-16.73,;15.28,-15.64,;14.73,-4.67,;16.06,-3.9,;16.06,-2.36,;14.73,-1.59,;14.75,-.05,;13.4,-2.36,;13.39,-3.9,)| | ||
Structure |