Reaction Details | |||
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Target | Mu-type opioid receptor | ||
Ligand | BDBM50122534 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_145593 (CHEMBL749738) | ||
IC50 | 2050±n/a nM | ||
Citation | Hanessian, S; Parthasarathy, S; Mauduit, M; Payza, K The power of visual imagery in drug design. Isopavines as a new class of morphinomimetics and their human opioid receptor binding activity. J Med Chem46:34-48 (2002) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Mu-type opioid receptor | |||
Name: | Mu-type opioid receptor | ||
Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 44789.51 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P35372 | ||
Residue: | 400 | ||
Sequence: |
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BDBM50122534 | |||
n/a | |||
Name | BDBM50122534 | ||
Synonyms: | 4,13-dibromo-17-cyclopropylmethyl-16-methyl-17-azatetracyclo[7.6.2.02,7.010,15]heptadeca-2(7),3,5,12,14-pentaene | ||
Type | Small organic molecule | ||
Emp. Form. | C21H23Br2N | ||
Mol. Mass. | 449.222 | ||
SMILES | C[C@@H]1[C@@H]2C3=CC(Br)=CC[C@H]3[C@H](Cc3ccc(Br)cc23)N1CC1CC1 |wU:2.2,10.21,9.8,1.0,c:6,t:3,TLB:0:1:3.9:18.12.11,17:18:19.1:3.9,THB:13:12:19.1:3.9,20:19:3.9:18.12.11,8:9:19.1:18.12.11,(10.17,-1.85,;8.73,-2.41,;4.99,-1.17,;4.98,.37,;4.98,1.93,;6.31,2.7,;6.31,4.24,;7.63,1.93,;7.65,.39,;6.31,-.4,;6.54,-4.25,;5,-4.25,;3.66,-3.48,;2.32,-4.25,;.99,-3.48,;.99,-1.94,;-.34,-1.17,;2.32,-1.17,;3.66,-1.94,;7.98,-3.74,;8.96,-4.92,;8.43,-6.37,;7.26,-7.35,;8.71,-7.89,)| | ||
Structure |