| Reaction Details |
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 | Report a problem with these data |
| Target | Cytosol aminopeptidase |
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| Ligand | BDBM50129682 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_98401 (CHEMBL881814) |
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| Ki | 74±n/a nM |
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| Citation |  Grembecka, J; Mucha, A; Cierpicki, T; Kafarski, P The most potent organophosphorus inhibitors of leucine aminopeptidase. Structure-based design, chemistry, and activity. J Med Chem46:2641-55 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cytosol aminopeptidase |
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| Name: | Cytosol aminopeptidase |
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| Synonyms: | AMPL_HUMAN | Aminopeptidase | LAP3 | LAPEP | Leucine aminopeptidase | PEPS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56171.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507539 |
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| Residue: | 519 |
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| Sequence: | MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFD
KLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKEN
IRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGS
GDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWI
EEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMD
LMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQV
DNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFE
ASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL
DIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA
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| BDBM50129682 |
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| n/a |
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| Name | BDBM50129682 |
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| Synonyms: | 2-[(1-Amino-3-phenyl-propyl)-hydroxy-phosphinoylmethyl]-4-methyl-pentanoic acid | CHEMBL327182 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H26NO4P |
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| Mol. Mass. | 327.3557 |
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| SMILES | CC(C)CC(CP(O)(O)C(=N)CCc1ccccc1)C(O)=O |
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| Structure | 
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