| Reaction Details |
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 | Report a problem with these data |
| Target | Hydroxycarboxylic acid receptor 2 |
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| Ligand | BDBM50132142 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_144336 (CHEMBL751847) |
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| Ki | 3540±n/a nM |
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| Citation |  van Herk, T; Brussee, J; van den Nieuwendijk, AM; van der Klein, PA; IJzerman, AP; Stannek, C; Burmeister, A; Lorenzen, A Pyrazole derivatives as partial agonists for the nicotinic acid receptor. J Med Chem46:3945-51 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hydroxycarboxylic acid receptor 2 |
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| Name: | Hydroxycarboxylic acid receptor 2 |
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| Synonyms: | Gpr109 | Gpr109a | Gpr109b | HCAR2_RAT | HM74 nicotinic acid GPCR | Hcar2 | Niacr1 | Pumag |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41476.06 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_820675 |
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| Residue: | 360 |
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| Sequence: | MSKQNHFLVINGKNCCVFRDENIAKVLPPVLGLEFVFGLLGNGLALWIFCFHLKSWKSSR
IFLFNLAVADFLLIICLPFLTDNYVQNWDWRFGSIPCRVMLFMLAMNRQGSIIFLTVVAV
DRYFRVVHPHHFLNKISNRTAAIISCFLWGITIGLTVHLLYTDMMTRNGDANLCSSFSIC
YTFRWHDAMFLLEFFLPLGIILFCSGRIIWSLRQRQMDRHVKIKRAINFIMVVAIVFVIC
FLPSVAVRIRIFWLLYKHNVRNCDIYSSVDLAFFTTLSFTYMNSMLDPVVYYFSSPSFPN
FFSTCINRCLRRKTLGEPDNNRSTSVELTGDPSTIRSIPGALMTDPSEPGSPPYLASTSR
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| BDBM50132142 |
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| n/a |
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| Name | BDBM50132142 |
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| Synonyms: | 4,5,6,7-Tetrahydro-1H-indazole-3-carboxylic acid | 4,5,6,7-tetrahydro-2H-indazole-3-carboxylic acid | CHEMBL338405 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H10N2O2 |
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| Mol. Mass. | 166.1772 |
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| SMILES | OC(=O)c1n[nH]c2CCCCc12 |
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| Structure | 
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