| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
|---|
| Ligand | BDBM50141018 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_106498 (CHEMBL713979) |
|---|
| EC50 | 0.380000±n/a nM |
|---|
| Citation |  Han, G; Haskell-Luevano, C; Kendall, L; Bonner, G; Hadley, ME; Cone, RD; Hruby, VJ De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach. J Med Chem47:1514-26 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocortin receptor 4 |
|---|
| Name: | Melanocortin receptor 4 |
|---|
| Synonyms: | MC4-R | MC4R_MOUSE | Mc4r |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 36964.43 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1498850 |
|---|
| Residue: | 332 |
|---|
| Sequence: | MNSTHHHGMYTSLHLWNRSSYGLHGNASESLGKGHPDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVS
GVLFIIYSDSSAVIICLISMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGTN
MKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPL
IYALRSQELRKTFKEIICFYPLGGICELSSRY
|
|
|
|---|
| BDBM50141018 |
|---|
| n/a |
|---|
| Name | BDBM50141018 |
|---|
| Synonyms: | 1N-(1-carbamoyl-2-hydroxypropyl)-7-[3-amino(imino)methylaminopropyl]-16-(1-amino-2-phenylethylcarboxamido)-10-benzyl-13-(1H-5-imidazolylmethyl)-4-(1H-3-indolylmethyl)-3,6,9,12,15,18-hexaoxo-2,5,8,11,14,19-hexaazacyclotricosane-1-carboxamide | CHEMBL414965 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C55H72N16O10 |
|---|
| Mol. Mass. | 1117.2614 |
|---|
| SMILES | C[C@@H](O)[C@H](NC(=O)[C@H]1CCCCNC(=O)C[C@H](NC(=O)[C@@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N1)C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
