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TargetMelanocyte-stimulating hormone receptor
LigandBDBM50141021
Substrate/Competitorn/a
Meas. Tech.ChEMBL_105856 (CHEMBL717326)
EC50 59.0±n/a nM
Citation Han, G; Haskell-Luevano, C; Kendall, L; Bonner, G; Hadley, ME; Cone, RD; Hruby, VJ De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach. J Med Chem47:1514-26 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melanocyte-stimulating hormone receptor
Name:Melanocyte-stimulating hormone receptor
Synonyms:MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r
Type:PROTEIN
Mol. Mass.:35238.60
Organism:Mus musculus
Description:ChEMBL_1498846
Residue:315
Sequence:
MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIA
ITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDV
LICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITY
YKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAAT
LTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRS
QELRMTLKEVLLCSW
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  Blast E-value cutoff:
BDBM50141021
n/a
NameBDBM50141021
Synonyms:1N-(1-carbamoyl-2-hydroxypropyl)-6-(1-amino-2-phenylethylcarboxamido)-15-(3-aminopropyl)-12-benzyl-9-(1H-5-imidazolylmethyl)-18-(1H-3-indolylmethyl)-5,5-dimethyl-7,10,13,16,19-pentaoxo-3,4-dithia-8,11,14,17,20-pentaazacycloicosane-1-carboxamide | CHEMBL2372365
TypeSmall organic molecule
Emp. Form.C52H67N13O9S2
Mol. Mass.1082.3
SMILESC[C@@H](O)[C@H](NC(=O)[C@H]1CSSC(C)(C)[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCN)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N1)C(N)=O
Structure
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