| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
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| Ligand | BDBM50141022 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105694 (CHEMBL718208) |
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| EC50 | 1±n/a nM |
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| Citation |  Han, G; Haskell-Luevano, C; Kendall, L; Bonner, G; Hadley, ME; Cone, RD; Hruby, VJ De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach. J Med Chem47:1514-26 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocyte-stimulating hormone receptor |
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| Name: | Melanocyte-stimulating hormone receptor |
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| Synonyms: | MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 34717.23 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q01726 |
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| Residue: | 317 |
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| Sequence: | MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVV
ATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVI
DVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFI
AYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGA
VTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAF
HSQELRRTLKEVLTCSW
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| BDBM50141022 |
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| n/a |
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| Name | BDBM50141022 |
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| Synonyms: | 1N-(1-carbamoyl-2-hydroxypropyl)-7-[3-amino(imino)methylaminopropyl]-16-(1-amino-2-phenylethylcarboxamido)-10-benzyl-4-(1H-3-indolylmethyl)-13-(2-methyl-1H-5-imidazolylmethyl)-3,6,9,12,15,19-hexaoxo-2,5,8,11,14,20-hexaazacyclotetracosane-1-carbox | CHEMBL427814 |
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| Type | Small organic molecule |
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| Emp. Form. | C57H76N16O10 |
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| Mol. Mass. | 1145.3145 |
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| SMILES | C[C@@H](O)[C@H](NC(=O)[C@H]1CCCCNC(=O)CC[C@H](NC(=O)[C@H](N)Cc2ccccc2)C(=O)N[C@@H](Cc2cnc(C)[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N1)C(N)=O |
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| Structure | 
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