| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
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| Ligand | BDBM50144873 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_106496 (CHEMBL717600) |
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| EC50 | 0.0870±n/a nM |
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| Citation |  Wilczynski, A; Wang, XS; Joseph, CG; Xiang, Z; Bauzo, RM; Scott, JW; Sorensen, NB; Shaw, AM; Millard, WJ; Richards, NG; Haskell-Luevano, C Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands. J Med Chem47:2194-207 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 4 |
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| Name: | Melanocortin receptor 4 |
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| Synonyms: | MC4-R | MC4R_MOUSE | Mc4r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36964.43 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1498850 |
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| Residue: | 332 |
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| Sequence: | MNSTHHHGMYTSLHLWNRSSYGLHGNASESLGKGHPDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVS
GVLFIIYSDSSAVIICLISMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGTN
MKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPL
IYALRSQELRKTFKEIICFYPLGGICELSSRY
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| BDBM50144873 |
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| n/a |
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| Name | BDBM50144873 |
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| Synonyms: | Ac-Nle-c[Asp-His-DPhe-Arg-Trp-Gly-Lys]-NH2 | CHEMBL216295 |
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| Type | Small organic molecule |
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| Emp. Form. | C50H69N15O10 |
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| Mol. Mass. | 1040.1774 |
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| SMILES | CC(C)C[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)ONCCCC[C@@H](NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O |
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| Structure | 
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