| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocortin receptor 3 |
|---|
| Ligand | BDBM50144880 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_106158 (CHEMBL718854) |
|---|
| EC50 | 309±n/a nM |
|---|
| Citation |  Wilczynski, A; Wang, XS; Joseph, CG; Xiang, Z; Bauzo, RM; Scott, JW; Sorensen, NB; Shaw, AM; Millard, WJ; Richards, NG; Haskell-Luevano, C Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands. J Med Chem47:2194-207 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocortin receptor 3 |
|---|
| Name: | Melanocortin receptor 3 |
|---|
| Synonyms: | MC3-R | MC3R_MOUSE | Mc3r |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 35808.24 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1498848 |
|---|
| Residue: | 323 |
|---|
| Sequence: | MNSSCCLSSVSPMLPNLSEHPAAPPASNRSGSGFCEQVFIKPEVFLALGIVSLMENILVI
LAVVRNGNLHSPMYFFLCSLAAADMLVSLSNSLETIMIAVINSDSLTLEDQFIQHMDNIF
DSMICISLVASICNLLAIAIDRYVTIFYALRYHSIMTVRKALTLIGVIWVCCGICGVMFI
IYSESKMVIVCLITMFFAMVLLMGTLYIHMFLFARLHVQRIAVLPPAGVVAPQQHSCMKG
AVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYA
FRSLELRNTFKEILCGCNSMNLG
|
|
|
|---|
| BDBM50144880 |
|---|
| n/a |
|---|
| Name | BDBM50144880 |
|---|
| Synonyms: | CHEMBL406032 | Tyr-c[Asp-His-Phe-Arg-Trp-Asn-Ala-Phe-Dpr]-Tyr-NH2 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C73H85N21O17 |
|---|
| Mol. Mass. | 1528.5865 |
|---|
| SMILES | C[C@@H]1NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@@H](CC(=O)NC(NC(=O)[C@@H](Cc2ccccc2)NC1=O)C(=O)NN[C@@H](Cc1ccc(O)cc1)C(=O)C(O)=O)NN[C@H]1Cc2ccc(O)cc2NC1=O |
|---|
| Structure | 
|
|---|
Search and Browse
