| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
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| Ligand | BDBM50144878 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_105855 (CHEMBL717325) |
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| EC50 | 1730±n/a nM |
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| Citation |  Wilczynski, A; Wang, XS; Joseph, CG; Xiang, Z; Bauzo, RM; Scott, JW; Sorensen, NB; Shaw, AM; Millard, WJ; Richards, NG; Haskell-Luevano, C Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands. J Med Chem47:2194-207 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocyte-stimulating hormone receptor |
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| Name: | Melanocyte-stimulating hormone receptor |
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| Synonyms: | MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35238.60 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1498846 |
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| Residue: | 315 |
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| Sequence: | MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIA
ITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDV
LICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITY
YKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAAT
LTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRS
QELRMTLKEVLLCSW
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| BDBM50144878 |
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| n/a |
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| Name | BDBM50144878 |
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| Synonyms: | CHEMBL402258 | Tyr-c[Asp-Arg-Phe-Phe-Asn-Ala-Phe-Dpr]-Tyr-NH2 |
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| Type | Small organic molecule |
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| Emp. Form. | C66H79N17O16 |
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| Mol. Mass. | 1366.4378 |
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| SMILES | C[C@@H]1NC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(=O)NC(NC(=O)C(=O)[C@@H](Cc2ccccc2)NC1=O)C(=O)NN[C@H](Cc1ccc(O)cc1)C(=O)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |
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| Structure | 
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