| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50150552 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302703 (CHEMBL839575) |
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| Ki | 4900±n/a nM |
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| Citation |  Hwang, YS; Chmielewski, J A unidirectional crosslinking strategy for HIV-1 protease dimerization inhibitors. Bioorg Med Chem Lett14:4297-300 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
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| BDBM50150552 |
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| n/a |
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| Name | BDBM50150552 |
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| Synonyms: | (E)-3-{(S)-1-[((S)-Carbamoyl-{11-[(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-methyl-butylcarbamoyl]-undecylcarbamoyl}-methyl)-carbamoyl]-2-phenyl-ethylcarbamoyl}-acrylic acid | CHEMBL364211 |
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| Type | Small organic molecule |
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| Emp. Form. | C43H61N7O9 |
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| Mol. Mass. | 819.9859 |
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| SMILES | CCC(C)[C@H](NC(=O)CCCCCCCCCCCNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)\C=C\C(O)=O)C(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
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| Structure | 
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