| Reaction Details |
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 | Report a problem with these data |
| Target | Trehalase |
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| Ligand | BDBM50156355 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304941 (CHEMBL826970) |
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| IC50 | 780000±n/a nM |
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| Citation |  Godin, G; Compain, P; Martin, OR; Ikeda, K; Yu, L; Asano, N Alpha-1-C-alkyl-1-deoxynojirimycin derivatives as potent and selective inhibitors of intestinal isomaltase: remarkable effect of the alkyl chain length on glycosidase inhibitory profile. Bioorg Med Chem Lett14:5991-5 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Trehalase |
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| Name: | Trehalase |
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| Synonyms: | Alpha,alpha-trehalase | Alpha,alpha-trehalose glucohydrolase | TREA | TREA_HUMAN | TREH |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66559.41 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_208276 |
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| Residue: | 583 |
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| Sequence: | MPGRTWELCLLLLLGLGLGSQEALPPPCESEIYCHGELLNQVQMAKLYQDDKQFVDMPLS
IAPEQVLQTFTELSRDHNHSIPREQLQAFVHEHFQAKGQELQPWTPADWKDSPQFLQKIS
DAKLRAWAGQLHQLWKKLGKKMKPEVLSHPERFSLIYSEHPFIVPGGRFVEFYYWDSYWV
MEGLLLSEMAETVKGMLQNFLDLVKTYGHVPNGGRVYYLQRSQPPLLTLMMDCYLTHTND
TAFLQENIETLALELDFWTKNRTVSVSLEGKNYLLNRYYVPYGGPRPESYSKDVELADTL
PEGDREALWAELKAGAESGWDFSSRWLIGGPNPNSLSGIRTSKLVPVDLNAFLCQAEELM
SNFYSRLGNDSQATKYRILRSQRLAALNTVLWDEQTGAWFDYDLEKKKKNREFYPSNLTP
LWAGCFSDPGVADKALKYLEDNRILTYQYGIPTSLQKTGQQWDFPNAWAPLQDLVIRGLA
KAPLRRAQEVAFQLAQNWIRTNFDVYSQKSAMYEKYDVSNGGQPGGGGEYEVQEGFGWTN
GVVLMLLDRYGDRLTSGAKLAFLEPHCLAATLLPSLLLSLLPW
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| BDBM50156355 |
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| n/a |
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| Name | BDBM50156355 |
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| Synonyms: | 2-Butyl-6-hydroxymethyl-piperidine-3,4,5-triol | CHEMBL365496 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H21NO4 |
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| Mol. Mass. | 219.278 |
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| SMILES | CCCCC1NC(CO)C(O)C(O)C1O |
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| Structure | 
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