| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Delta-type opioid receptor |
|---|
| Ligand | BDBM50166351 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_305139 |
|---|
| IC50 | 36±n/a nM |
|---|
| Citation |  Mollica, A; Davis, P; Ma, SW; Lai, J; Porreca, F; Hruby, VJ Synthesis and biological evaluation of new biphalin analogues with non-hydrazine linkers. Bioorg Med Chem Lett15:2471-5 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Delta-type opioid receptor |
|---|
| Name: | Delta-type opioid receptor |
|---|
| Synonyms: | DOR-1 | K56 | MSL-2 | OPIATE Delta | OPRD_MOUSE | Opioid receptors; mu and delta | Oprd1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 40577.25 |
|---|
| Organism: | MOUSE |
|---|
| Description: | P32300 |
|---|
| Residue: | 372 |
|---|
| Sequence: | MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA
|
|
|
|---|
| BDBM50166351 |
|---|
| n/a |
|---|
| Name | BDBM50166351 |
|---|
| Synonyms: | 2-Amino-N-((S)-1-{[(1-{(S)-4-[(R)-2-(2-{2-[1-amino-2-((R)-4-hydroxy-phenyl)-ethylamino]-propionylamino}-acetylamino)-3-(S)-phenyl-propionylamino]-phenylcarbamoyl}-2-phenyl-ethylcarbamoyl)-methyl]-carbamoyl}-ethyl)-3-(4-hydroxy-phenyl)-propionamide; ditrifluoroacetic acid | CHEMBL262490 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C51H60N10O9 |
|---|
| Mol. Mass. | 957.0837 |
|---|
| SMILES | C[C@H](N[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@H](Cc1ccccc1)C(=O)Nc1ccc(NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
