| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50152076 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302928 (CHEMBL830387) |
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| Ki | 4200±n/a nM |
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| Citation |  Elzein, E; Palle, V; Wu, Y; Maa, T; Zeng, D; Zablocki, J 2-Pyrazolyl-N(6)-substituted adenosine derivatives as high affinity and selective adenosine A(3) receptor agonists. J Med Chem47:4766-73 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50152076 |
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| n/a |
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| Name | BDBM50152076 |
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| Synonyms: | 2-Hydroxymethyl-5-[6-(3-iodo-benzylamino)-2-(4-pyridin-2-yl-pyrazol-1-yl)-purin-9-yl]-tetrahydro-furan-3,4-diol | CHEMBL362117 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H23IN8O4 |
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| Mol. Mass. | 626.4058 |
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| SMILES | OC[C@H]1OC([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)nc(nc12)-n1cc(cn1)-c1ccccn1 |
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| Structure | 
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