| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosylhomocysteinase |
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| Ligand | BDBM50370520 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302948 (CHEMBL841783) |
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| Ki | 550±n/a nM |
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| Citation |  Wnuk, SF; Lewandowska, E; Sacasa, PR; Crain, LN; Zhang, J; Borchardt, RT; De Clercq, E Stereoselective synthesis of sugar-modified enyne analogues of adenosine and uridine. Interaction with S-adenosyl-L-homocysteine hydrolase and antiviral and cytotoxic effects. J Med Chem47:5251-7 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosylhomocysteinase |
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| Name: | Adenosylhomocysteinase |
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| Synonyms: | AHCY | Adenosylhomocysteinase | SAHH | SAHH_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47714.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1507791 |
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| Residue: | 432 |
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| Sequence: | MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVET
AVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYF
KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINV
NDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVI
ITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIG
HFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSN
SFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMS
CDGPFKPDHYRY
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| BDBM50370520 |
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| n/a |
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| Name | BDBM50370520 |
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| Synonyms: | CHEMBL611098 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13N5O3 |
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| Mol. Mass. | 287.274 |
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| SMILES | Nc1ncnc2n(cnc12)C1O[C@H](\C=C\C#C)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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