Reaction Details | |||
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Target | Acetylcholinesterase | ||
Ligand | BDBM50117578 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_305174 (CHEMBL832763) | ||
IC50 | 100±n/a nM | ||
Citation | Guo, J; Hurley, MM; Wright, JB; Lushington, GH A docking score function for estimating ligand-protein interactions: application to acetylcholinesterase inhibition. J Med Chem47:5492-500 (2004) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Acetylcholinesterase | |||
Name: | Acetylcholinesterase | ||
Synonyms: | ACES_HUMAN | ACHE | Acetylcholinesterase (AChE) | Acetylcholinesterase (human AChE) | ||
Type: | Enzyme | ||
Mol. Mass.: | 67792.70 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P22303 | ||
Residue: | 614 | ||
Sequence: |
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BDBM50117578 | |||
n/a | |||
Name | BDBM50117578 | ||
Synonyms: | 1-Benzyl-4-[3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-3-oxo-propyl]-1-methyl-piperidinium | CHEMBL86031 | ||
Type | Small organic molecule | ||
Emp. Form. | C24H30NO3 | ||
Mol. Mass. | 380.4994 | ||
SMILES | C[N+]1(Cc2ccccc2)CCC(CCC(=O)c2ccc3OCCOc3c2)CC1 |(20.14,-5.28,;19.05,-6.38,;20.38,-7.15,;21.72,-6.38,;23.05,-7.15,;24.38,-6.38,;24.38,-4.84,;23.04,-4.07,;21.71,-4.84,;19.05,-4.84,;17.74,-4.07,;16.4,-4.83,;15.14,-4.18,;13.73,-4.81,;12.48,-3.9,;12.65,-2.36,;11.07,-4.53,;10.92,-6.05,;9.52,-6.68,;8.26,-5.79,;6.84,-6.42,;5.58,-5.49,;5.75,-3.94,;7.19,-3.32,;8.43,-4.25,;9.83,-3.62,;16.39,-6.37,;17.72,-7.15,)| | ||
Structure |