| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50326662 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_305140 (CHEMBL832435) |
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| IC50 | 2±n/a nM |
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| Citation |  Lattanzi, R; Spetea, M; Schüllner, F; Rief, SB; Krassnig, R; Negri, L; Schmidhammer, H Synthesis and biological evaluation of 14-alkoxymorphinans. 22.(1) Influence of the 14-alkoxy group and the substitution in position 5 in 14-alkoxymorphinan-6-ones on in vitro and in vivo activities. J Med Chem48:3372-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 11165.58 |
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| Organism: | GUINEA PIG |
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| Description: | P97266 |
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| Residue: | 98 |
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| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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| BDBM50326662 |
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| n/a |
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| Name | BDBM50326662 |
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| Synonyms: | 10-hydroxy-17-methoxy-4-methyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one | CHEMBL607405 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21NO4 |
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| Mol. Mass. | 315.3636 |
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| SMILES | CO[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(C)CC[C@@]235)ccc4O |r| |
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| Structure | 
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