| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Guanine nucleotide-binding protein G(i) subunit alpha-1 |
|---|
| Ligand | BDBM50174662 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_321104 (CHEMBL882870) |
|---|
| EC50 | 21100±n/a nM |
|---|
| Citation |  Manetti, D; Di Cesare Mannelli, L; Dei, S; Galeotti, N; Ghelardini, C; Romanelli, MN; Scapecchi, S; Teodori, E; Pacini, A; Bartolini, A; Gualtieri, F Design, synthesis, and preliminary pharmacological evaluation of a set of small molecules that directly activate gi proteins. J Med Chem48:6491-503 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Guanine nucleotide-binding protein G(i) subunit alpha-1 |
|---|
| Name: | Guanine nucleotide-binding protein G(i) subunit alpha-1 |
|---|
| Synonyms: | GNAI1 | GNAI1_HUMAN | Guanine nucleotide-binding protein G(i), alpha-1 subunit |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 40357.62 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_321104 |
|---|
| Residue: | 354 |
|---|
| Sequence: | MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG
YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT
AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVK
TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA
AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
|
|
|
|---|
| BDBM50174662 |
|---|
| n/a |
|---|
| Name | BDBM50174662 |
|---|
| Synonyms: | 1-Tridecyl-[4,4']bipiperidinyl; dihydrochloride | CHEMBL537416 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H46N2 |
|---|
| Mol. Mass. | 350.6247 |
|---|
| SMILES | CCCCCCCCCCCCCN1CCC(CC1)C1CCNCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
