| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-amylase |
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| Ligand | BDBM50174835 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_326643 (CHEMBL868728) |
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| IC50 | 247300±n/a nM |
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| Citation |  Seo, WD; Kim, JH; Kang, JE; Ryu, HW; Curtis-Long, MJ; Lee, HS; Yang, MS; Park, KH Sulfonamide chalcone as a new class of alpha-glucosidase inhibitors. Bioorg Med Chem Lett15:5514-6 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-amylase |
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| Name: | Beta-amylase |
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| Synonyms: | AMYB | AMYB_HORVU | BMY1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 59640.69 |
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| Organism: | Hordeum vulgare |
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| Description: | ChEMBL_326643 |
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| Residue: | 535 |
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| Sequence: | MEVNVKGNYVQVYVMLPLDAVSVNNRFEKGDELRAQLRKLVEAGVDGVMVDVWWGLVEGK
GPKAYDWSAYKQLFELVQKAGLKLQAIMSFHQCGGNVGDAVNIPIPQWVRDVGTRDPDIF
YTDGHGTRNIEYLTLGVDNQPLFHGRSAVQMYADYMTSFRENMKDFLDAGVIVDIEVGLG
PAGEMRYPSYPQSHGWSFPGIGEFICYDKYLQADFKAAAAAVGHPEWEFPNDVGQYNDTP
ERTQFFRDNGTYLSEKGRFFLAWYSNNLIKHGDRILDEANKVFLGYKVQLAIKISGIHWW
YKVPSHAAELTAGYYNLHDRDGYRTIARMLKRHRASINFTCAEMRDLEQSSQAMSAPEEL
VQQVLSAGWREGLNVACENALPRYDPTAYNTILRNARPHGINQSGPPEHKLFGFTYLRLS
NQLVEGQNYVNFKTFVDRMHANLPRDPYVDPMAPLPRSGPEISIEMILQAAQPKLQPFPF
QEHTDLPVGPTGGMGGQAEGPTCGMGGQVKGPTGGMGGQAEDPTSGIGGELPATM
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| BDBM50174835 |
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| n/a |
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| Name | BDBM50174835 |
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| Synonyms: | 4'-(4-toluenesulfonamido)-4-hydroxychalcone | 4'-(p-Toluenesulfonamide)-4-hydroxychalcone | CHEMBL371723 | N-(4-(3-(4-hydroxyphenyl)acryloyl)phenyl)-4-methylbenzenesulfonamide | Sulfonamide chalcone, 4 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H19NO4S |
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| Mol. Mass. | 393.456 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)cc1 |
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| Structure | 
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