| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-amylase |
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| Ligand | BDBM50174839 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_326642 (CHEMBL868756) |
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| IC50 | 268900±n/a nM |
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| Citation |  Seo, WD; Kim, JH; Kang, JE; Ryu, HW; Curtis-Long, MJ; Lee, HS; Yang, MS; Park, KH Sulfonamide chalcone as a new class of alpha-glucosidase inhibitors. Bioorg Med Chem Lett15:5514-6 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-amylase |
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| Name: | Alpha-amylase |
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| Synonyms: | AMY_BACLI | amyL | amyS |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58553.00 |
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| Organism: | Bacillus licheniformis |
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| Description: | ChEMBL_326642 |
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| Residue: | 512 |
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| Sequence: | MKQQKRLYARLLTLLFALIFLLPHSAAAAANLNGTLMQYFEWYMPNDGQHWKRLQNDSAY
LAEHGITAVWIPPAYKGTSQADVGYGAYDLYDLGEFHQKGTVRTKYGTKGELQSAIKSLH
SRDINVYGDVVINHKGGADATEDVTAVEVDPADRNRVISGEHRIKAWTHFHFPGRGSTYS
DFKWHWYHFDGTDWDESRKLNRIYKFQGKAWDWEVSNENGNYDYLMYADIDYDHPDVAAE
IKRWGTWYANELQLDGFRLDAVKHIKFSFLRDWVNHVREKTGKEMFTVAEYWQNDLGALE
NYLNKTNFNHSVFDVPLHYQFHAASTQGGGYDMRKLLNSTVVSKHPLKAVTFVDNHDTQP
GQSLESTVQTWFKPLAYAFILTRESGYPQVFYGDMYGTKGDSQREIPALKHKIEPILKAR
KQYAYGAQHDYFDHHDIVGWTREGDSSVANSGLAALITDGPGGAKRMYVGRQNAGETWHD
ITGNRSEPVVINSEGWGEFHVNGGSVSIYVQR
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| BDBM50174839 |
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| n/a |
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| Name | BDBM50174839 |
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| Synonyms: | 1-(4-aminophenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one | 4'-Amino-4-hydroxychalcone | CHEMBL383563 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H13NO2 |
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| Mol. Mass. | 239.2692 |
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| SMILES | Nc1ccc(cc1)C(=O)\C=C\c1ccc(O)cc1 |
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| Structure | 
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