| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Estrogen receptor |
|---|
| Ligand | BDBM50178322 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_332769 (CHEMBL865276) |
|---|
| IC50 | >1000±n/a nM |
|---|
| Citation |  Blizzard, TA; Gude, C; Morgan, JD; Chan, W; Birzin, ET; Mojena, M; Tudela, C; Chen, F; Knecht, K; Su, Q; Kraker, B; Mosley, RT; Holmes, MA; Sharma, N; Fitzgerald, PM; Rohrer, SP; Hammond, ML Androstenediol analogs as ER-beta-selective SERMs. Bioorg Med Chem Lett16:834-8 (2006) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Estrogen receptor |
|---|
| Name: | Estrogen receptor |
|---|
| Synonyms: | ER | ER-alpha | ESR | ESR1 | ESR1_HUMAN | Estradiol receptor | Estrogen receptor | Estrogen receptor (ER alpha) | Estrogen receptor (ER-alpha) | Estrogen receptor alpha (ER alpha) | Estrogen receptor alpha (ER) | NR3A1 | Nuclear receptor subfamily 3 group A member 1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 66230.44 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P03372 |
|---|
| Residue: | 595 |
|---|
| Sequence: | MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
|
|
|
|---|
| BDBM50178322 |
|---|
| n/a |
|---|
| Name | BDBM50178322 |
|---|
| Synonyms: | 2-((3S,10S,13S,17S)-3,17-dihydroxy-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-10-yl)acetaldehyde | CHEMBL201364 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H30O3 |
|---|
| Mol. Mass. | 318.4504 |
|---|
| SMILES | C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34CC=O)C1CC[C@@H]2O |t:7| |
|---|
| Structure | 
|
|---|
Search and Browse
