Ki Summary

Reaction Details

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Target

P2Y purinoceptor 1

Ligand

BDBM50184369

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_338251 (CHEMBL867177)

EC50

800±n/a nM

Citation

Nahum, V; Tulapurkar, M; Lévesque, SA; Sévigny, J; Reiser, G; Fischer, B Diadenosine and diuridine poly(borano)phosphate analogues: synthesis, chemical and enzymatic stability, and activity at P2Y1 and P2Y2 receptors. J Med Chem49:1980-90 (2006) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

P2Y purinoceptor 1

Name:

P2Y purinoceptor 1

Synonyms:

Type:

Enzyme

Mol. Mass.:

42090.25

Organism:

Homo sapiens (Human)

Description:

P47900

Residue:

373

Sequence:

MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYIL
VFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFG
DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVV
VAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLI
VRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFND
RVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLN
ILPEFKQNGDTSL

BDBM50184369

n/a

Name

BDBM50184369

Synonyms:

CHEMBL413131 | pentakis(tributylamine) boranuidyl({[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphinato]oxy})phosphoryl ({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate

Type

Small organic molecule

Emp. Form.

C18H25BN4O25P5

Mol. Mass.

863.085

SMILES

[BH3-]P(=O)(OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O)OP([O-])(=O)OP([O-])(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O

Structure