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Target3-oxoacyl-acyl-carrier protein reductase
LigandBDBM15236
Substrate/Competitorn/a
Meas. Tech.ChEMBL_361105 (CHEMBL859171)
IC50 14000±n/a nM
Citation Tasdemir, DLack, GBrun, RRüedi, PScapozza, LPerozzo, R Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. J Med Chem49:3345-53 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
3-oxoacyl-acyl-carrier protein reductase
Name:3-oxoacyl-acyl-carrier protein reductase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:33333.53
Organism:Plasmodium falciparum
Description:ChEMBL_675156
Residue:301
Sequence:
MSVLHRFYLFFLFTKFFHCYKISYVLKNAKLAPNHAIKNINSLNLLSENKKENYYYCGEN
KVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDVSK
KEEISEVINKILTEHKNVDILVSNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQPIS
KRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAPG
FISSDMTDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFVIDGGLS
P
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  Blast E-value cutoff:
BDBM15236
n/a
NameBDBM15236
Synonyms:3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one | 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one | CHEMBL164 | Cannabiscetin | Myricetin | Myricetin (20) | Myricetin (Myr) | cid_5281672
TypeSmall organic molecule
Emp. Form.C15H10O8
Mol. Mass.318.2351
SMILESOc1cc(O)c2c(c1)oc(-c1cc(O)c(O)c(O)c1)c(O)c2=O
Structure
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