| Reaction Details |
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 | Report a problem with these data |
| Target | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
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| Ligand | BDBM26664 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_361103 (CHEMBL859169) |
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| IC50 | 20000±n/a nM |
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| Citation |  Tasdemir, D; Lack, G; Brun, R; Rüedi, P; Scapozza, L; Perozzo, R Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. J Med Chem49:3345-53 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
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| Name: | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase |
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| Synonyms: | Fatty acid synthase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26222.50 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_983601 |
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| Residue: | 230 |
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| Sequence: | MRFLIIHIAVIVLPFVLMIDVKRENSFFLRHSPKRLYKKADYNNMYDKIIKKQQNRIYDV
SSQINQDNINGQNISFNLTFPNYDTSIDIEDIKKILPHRYPFLLVDKVIYMQPNKTIIGL
KQVSTNEPFFNGHFPQKQIMPGVLQIEALAQLAGILCLKSDDSQKNNLFLFAGVDGVRWK
KPVLPGDTLTMQANLISFKSSLGIAKLSGVGYVNGKVVINISEMTFALSK
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| BDBM26664 |
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| n/a |
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| Name | BDBM26664 |
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| Synonyms: | 7-Hydroxy-flavone, 5a | 7-Hydroxyflavone, 11 | 7-hydroxy-2-phenyl-4H-chromen-4-one | 7-hydroxyflavone | CHEMBL276915 |
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| Type | Flavonoid |
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| Emp. Form. | C15H10O3 |
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| Mol. Mass. | 238.2381 |
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| SMILES | Oc1ccc2c(c1)oc(cc2=O)-c1ccccc1 |
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| Structure | 
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