| Reaction Details |
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 | Report a problem with these data |
| Target | 3-oxoacyl-acyl-carrier protein reductase |
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| Ligand | BDBM50049391 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_361105 (CHEMBL859171) |
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| IC50 | 100000±n/a nM |
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| Citation |  Tasdemir, D; Lack, G; Brun, R; Rüedi, P; Scapozza, L; Perozzo, R Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids. J Med Chem49:3345-53 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-oxoacyl-acyl-carrier protein reductase |
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| Name: | 3-oxoacyl-acyl-carrier protein reductase |
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| Synonyms: | n/a |
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| Type: | PROTEIN |
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| Mol. Mass.: | 33333.53 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_675156 |
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| Residue: | 301 |
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| Sequence: | MSVLHRFYLFFLFTKFFHCYKISYVLKNAKLAPNHAIKNINSLNLLSENKKENYYYCGEN
KVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGYAGDVSK
KEEISEVINKILTEHKNVDILVSNAGITRDNLFLRMKNDEWEDVLRTNLNSLFYITQPIS
KRMINNRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAPG
FISSDMTDKISEQIKKNIISNIPAGRMGTPEEVANLACFLSSDKSGYINGRVFVIDGGLS
P
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| BDBM50049391 |
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| n/a |
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| Name | BDBM50049391 |
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| Synonyms: | 3,5,7-Trihydroxyflavone | 3,5,7-triOH-flavone | 3,5,7-trihydroxy-2-phenyl-4H-benzopyran-4-one | 3,5,7-trihydroxy-2-phenyl-4H-chromen-4-one | CHEMBL309490 | Galangin | Galangin (15) | Galangin (Gal) | cid_5281616 | norizalpinin |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10O5 |
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| Mol. Mass. | 270.2369 |
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| SMILES | Oc1cc(O)c2c(c1)oc(-c1ccccc1)c(O)c2=O |
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| Structure | 
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