| Reaction Details |
|---|
 | Report a problem with these data |
| Target | L-selectin |
|---|
| Ligand | BDBM50205404 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_428319 (CHEMBL917097) |
|---|
| IC50 | 14600±n/a nM |
|---|
| Citation |  Kranich, R; Busemann, AS; Bock, D; Schroeter-Maas, S; Beyer, D; Heinemann, B; Meyer, M; Schierhorn, K; Zahlten, R; Wolff, G; Aydt, EM Rational design of novel, potent small molecule pan-selectin antagonists. J Med Chem50:1101-15 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| L-selectin |
|---|
| Name: | L-selectin |
|---|
| Synonyms: | LNHR | LYAM1 | LYAM1_HUMAN | Leukocyte adhesion molecule-1 | SELL | Selectin |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 42187.20 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_200000 |
|---|
| Residue: | 372 |
|---|
| Sequence: | MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDN
YTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPN
NKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTC
NCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETT
CGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKK
TICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKK
GKKSKRSMNDPY
|
|
|
|---|
| BDBM50205404 |
|---|
| n/a |
|---|
| Name | BDBM50205404 |
|---|
| Synonyms: | (5-{2-[2-(2,3,4-trihydroxy-phenyl)-acetylamino]-phenyl}-thiophen-2-yl)-acetic acid | CHEMBL220776 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H17NO6S |
|---|
| Mol. Mass. | 399.417 |
|---|
| SMILES | OC(=O)Cc1ccc(s1)-c1ccccc1NC(=O)Cc1ccc(O)c(O)c1O |
|---|
| Structure | 
|
|---|
Search and Browse
