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TargetC-C chemokine receptor type 2
LigandBDBM50196700
Substrate/Competitorn/a
Meas. Tech.ChEMBL_432048 (CHEMBL918245)
IC50 19000±n/a nM
Citation Iwakubo, M; Takami, A; Okada, Y; Kawata, T; Tagami, Y; Ohashi, H; Sato, M; Sugiyama, T; Fukushima, K; Iijima, H Design and synthesis of Rho kinase inhibitors (II). Bioorg Med Chem15:350-64 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
C-C chemokine receptor type 2
Name:C-C chemokine receptor type 2
Synonyms:C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1)
Type:Enzyme
Mol. Mass.:41932.32
Organism:Homo sapiens (Human)
Description:P41597
Residue:374
Sequence:
MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN
MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY
HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK
CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR
AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI
NPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSI
GRAPEASLQDKEGA
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BDBM50196700
n/a
NameBDBM50196700
Synonyms:5-((3-(3-(prop-1-en-2-yl)benzyl)cyclohexyl)methyl)-1H-indene | CHEMBL224594 | N-[1-(3-nitrobenzyl)-3-piperidyl]-N-(1H-5-indazolyl)amine
TypeSmall organic molecule
Emp. Form.C19H21N5O2
Mol. Mass.351.4023
SMILES[O-][N+](=O)c1cccc(CN2CCCC(C2)Nc2ccc3[nH]ncc3c2)c1
Structure
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