| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 2 |
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| Ligand | BDBM50196690 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_432048 (CHEMBL918245) |
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| IC50 | 2000±n/a nM |
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| Citation |  Iwakubo, M; Takami, A; Okada, Y; Kawata, T; Tagami, Y; Ohashi, H; Sato, M; Sugiyama, T; Fukushima, K; Iijima, H Design and synthesis of Rho kinase inhibitors (II). Bioorg Med Chem15:350-64 (2006) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 2 |
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| Name: | C-C chemokine receptor type 2 |
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| Synonyms: | C-C chemokine receptor type 2 (CCR2) | CCR2 | CCR2_HUMAN | CMKBR2 | Chemoattractant Cytokine Receptor 2 (CCR2) | Chemokine Receptor Type 2b (CCR2b) | Monocyte chemotactic protein-1 (MCP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41932.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41597 |
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| Residue: | 374 |
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| Sequence: | MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN
MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY
HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK
CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR
AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI
NPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSI
GRAPEASLQDKEGA
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| BDBM50196690 |
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| n/a |
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| Name | BDBM50196690 |
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| Synonyms: | CHEMBL224535 | N-(1-(4-aminobenzyl)piperidin-3-yl)-1H-indazol-5-amine | N-[1-(4-aminobenzyl)-3-piperidyl]-N-(1H-5-indazolyl)amine |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23N5 |
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| Mol. Mass. | 321.4194 |
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| SMILES | Nc1ccc(CN2CCCC(C2)Nc2ccc3[nH]ncc3c2)cc1 |
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| Structure | 
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