| Reaction Details |
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 | Report a problem with these data |
| Target | Transporter |
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| Ligand | BDBM50212359 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_436642 (CHEMBL904952) |
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| Ki | 28±n/a nM |
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| Citation |  Kim, DI; Deutsch, HM; Ye, X; Schweri, MM Synthesis and pharmacology of site-specific cocaine abuse treatment agents: restricted rotation analogues of methylphenidate. J Med Chem50:2718-31 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transporter |
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| Name: | Transporter |
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| Synonyms: | Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66787.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1463061 |
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| Residue: | 597 |
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| Sequence: | MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLF
YMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLN
LPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDI
GLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNG
INAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTIN
CVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFL
MLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLT
LLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLL
FVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAY
GITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
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| BDBM50212359 |
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| n/a |
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| Name | BDBM50212359 |
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| Synonyms: | CHEMBL558182 | threo-1-aza-4beta-hydroxy-5-(3,4-dichlorophenyl)[4.4.0]decane hydrochloride |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19Cl2NO |
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| Mol. Mass. | 300.223 |
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| SMILES | O[C@H]1CCN2CCCC[C@@H]2[C@H]1c1ccc(Cl)c(Cl)c1 |
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| Structure | 
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